Effective HIV-1 protease inhibitors should have all of the following characteristics (mark all the correct answers): effective delivery in sufficient quantities to the desired site(s) of action in the organism. relative specificity for the HIV-1 protease. a backbone –OH group that forms a weak association with the two active-site carboxyl groups of the protease. results in inhibiting the production of new virus particles in cells of infected patients. broad spectrum enough to be effective against mutant viral forms.